These are the ones I listen to regularly:
Stuff you should know (from howstuffworks)
Stuff you missed in History Class (from howstuffworks)
Wait Wait Don't tell me (comedy/news thing from NPR)
The Totally Rad Show (movies, video games)
Skeptics Guide to the Universe (science news, but falls into your Radio dislike criteria above)
ROFL has decent standup comedy, but its pretty short, maybe a minute or two for 7-8 comedians back to back. Kind of hit or miss though.
I have yet to find a single sports podcast that I like, the only decent ones are always a couple days behind on what I already know is going on in sports by the time they publish.