I haven't built a computer in soooo long. I usually just go mainstream... and then gut the software and reinstall the OS and drivers.
But I am not doing any high end stuff like I bet you do. My office computer blew up last year. I have been using the computer in the family room to check email / log into work.... and lately my Mac mini on the TV for everything else.
I think I might actually ditch the PC approach (since I have so many at work anyway) and go with an iMac for the home office. I can always Citrix in to any kind of virtual desktop I want (Windows 8, Windows 7, XP, Servers...etc etc).
You have any experience with Macs?